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Updated: Jul 7, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Thrombus development on a transseptal sheath in the right atrium before electrical pulmonary vein isolation
Nieves Romero-Rodriguez1, Alonso Pedrote, Eduardo Arana-Rueda
1Arrhythmia Unit. Hospital Virgen del Rocio, Seville, Spain. niemed21@hotmail.com
Insights
A thrombus on a transseptal sheath was identified in the right atrium during atrial fibrillation treatment. Intracardiac echocardiography likely prevented a major thromboembolic event.
Area of Science:
- Cardiology
- Medical Imaging
- Electrophysiology
Background:
- Atrial fibrillation is a common arrhythmia requiring treatment.
- Transseptal puncture is a key procedure for atrial fibrillation ablation.
- Thromboembolic complications are a risk during cardiac procedures.
Purpose of the Study:
- To report a case of thrombus formation on a transseptal sheath.
- To highlight the utility of intracardiac echocardiography in identifying intraprocedural complications.
- To emphasize the potential for preventing thromboembolic events.
Main Methods:
- Case report of a patient undergoing circumferential pulmonary vein isolation.
- Utilized intracardiac echocardiography for real-time imaging during the procedure.
- Described the identification and management of an unexpected finding.
Main Results:
- A thrombus was identified on the transseptal sheath within the right atrium prior to transseptal puncture.
- Intracardiac echocardiography provided clear visualization of the thrombus.
- The finding potentially averted a significant thromboembolic complication.
Conclusions:
- Transseptal sheath thrombus is a rare but serious complication.
- Intracardiac echocardiography is invaluable for detecting such intraprocedural risks.
- Early detection and intervention can prevent major adverse events during atrial fibrillation ablation.
Abstract:
We describe the case of a patient who developed a thrombus on the transseptal sheath in the right atrium before transseptal puncture for circumferential pulmonary vein isolation for paroxysmal atrial fibrillation treatment. The use of intracardiac echocardiography allowed to its identification and probably prevented the patient from suffering a serious thromboembolic complication.
Related Concept Videos
Venous Thrombosis I: Introduction
Cardiac Catheterization II: Right Heart Catheterization
Pulmonary Embolism I: Introduction
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Venous Thrombosis III: Interprofessional Care

