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Depression symptoms during pregnancy.

R Manber1, C Blasey, J J B Allen

  • 1Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, California 94305, USA. Rmanber@stanford.edu

Archives of Women'S Mental Health
|February 14, 2008
PubMed
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Depression symptoms in pregnant women with major depressive disorder (MDD) are similar to non-pregnant women, with key differences in specific symptom presentations. These psychological symptoms require serious attention, not dismissal as normal pregnancy changes.

Area of Science:

  • Psychiatry
  • Obstetrics
  • Women's Health

Background:

  • Major depressive disorder (MDD) symptoms can be altered by pregnancy.
  • The specific presentation of depression during pregnancy compared to other life stages is not well understood.

Purpose of the Study:

  • To compare the severity and profile of depressive symptoms in pregnant women with MDD to non-pregnant women with MDD and pregnant women without MDD.

Main Methods:

  • Cross-sectional study comparing three groups: pregnant women with MDD (PD), non-pregnant women with MDD (D), and pregnant women without MDD (P).
  • Symptom severity was assessed using standardized measures, comparing overall severity and individual symptom scores across groups.

Main Results:

  • Pregnant women with MDD (PD) showed similar overall depression severity to non-pregnant depressed women (D).

Related Experiment Videos

  • PD women had lower scores for suicidality, guilt, and early insomnia, but higher scores for psychomotor retardation compared to D women.
  • Both depressed groups (PD and D) had significantly higher symptom severity than the non-depressed pregnant group (P), with smaller effect sizes for somatic symptoms compared to psychological symptoms.

    • Conclusions:

    • The symptom profile of major depressive disorder during pregnancy is largely comparable to that in non-pregnant women.
    • Psychological symptoms of depression during pregnancy warrant serious clinical attention and should not be attributed to normal pregnancy experiences.