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Related Concept Videos

Bipolar Disorder01:30

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
Borderline Personality Disorder01:25

Borderline Personality Disorder

Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
Dark Triad and Person Perception01:29

Dark Triad and Person Perception

Person perception is influenced by both external behaviors and the observer’s internal characteristics, including personality traits. Individuals with dark personality traits, comprising psychopathy, Machiavellianism, and narcissism — collectively known as the dark triad – exhibit manipulative and exploitative tendencies in social contexts. These traits affect how they perceive others and how they are perceived.The Role of Dark Personality Traits in Person PerceptionBlack et al. (2014) explored...
Aggression01:47

Aggression

Humans engage in aggression when they seek to cause harm or pain to another person. Aggression takes two forms depending on one’s motives: hostile or instrumental. Hostile aggression is motivated by feelings of anger with intent to cause pain; a fight in a bar with a stranger is an example of hostile aggression. In contrast, instrumental aggression is motivated by achieving a goal and does not necessarily involve intent to cause pain (Berkowitz, 1993); a contract killer who murders for hire...
Antisocial Personality Disorder01:24

Antisocial Personality Disorder

Antisocial personality disorder is a chronic mental health condition characterized by persistent patterns of disregard for the rights and well-being of others. Individuals with antisocial personality disorder exhibit behaviors that include deceitfulness, impulsivity, irresponsibility, aggression, and a profound lack of empathy. These traits often manifest early in life and persist into adulthood, leading to significant personal, social, and legal consequences.
Behavioral Characteristics and...
Bullying02:04

Bullying

A modern form of aggression is bullying. As you learn in your study of child development, socializing and playing with other children is beneficial for children’s psychological development. However, as you may have experienced as a child, not all play behavior has positive outcomes. Some children are aggressive and want to play roughly. Other children are selfish and do not want to share toys. One form of negative social interactions among children that has become a national concern is bullying.

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Related Experiment Video

Updated: Jul 7, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

Predictors of trait aggression in bipolar disorder.

Jessica L Garno1, Nisali Gunawardane, Joseph F Goldberg

  • 1Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, New York, NY 11004, USA. jgarno@nshs.edu

Bipolar Disorders
|February 15, 2008
PubMed
Summary

Trait aggression in bipolar disorder (BD) is predicted by comorbid borderline personality disorder and current manic and depressive symptoms. These findings highlight the importance of considering personality disorders in BD treatment.

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The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress
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Last Updated: Jul 7, 2026

Developing a Rat Model for Bipolar Disorder
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The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress
09:12

The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress

Published on: July 4, 2013

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Neuroscience

Background:

  • Aggressive behavior is frequently observed in Bipolar Disorder (BD).
  • The relationship between aggression and BD is complex, potentially influenced by developmental factors and comorbid conditions.
  • Distinguishing aggression intrinsic to BD versus that stemming from comorbidities is crucial for understanding its underlying biological mechanisms.

Purpose of the Study:

  • To identify predictors of trait aggression in adults diagnosed with Bipolar Disorder.
  • To clarify whether aggression in BD is primarily linked to the disorder itself or to co-occurring conditions.

Main Methods:

  • One hundred adult patients with Bipolar I or II disorder were evaluated.
  • Diagnoses were confirmed using the Structured Clinical Interview for DSM-IV (SCID-I) and SCID-II.
  • Symptom severity was assessed using the Hamilton Depression Rating Scale (HDRS) and Young Mania Rating Scale (YMRS). Childhood maltreatment was measured by the Childhood Trauma Questionnaire (CTQ), and trait aggression by the Brown-Goodwin Aggression Scale (BGA).

Main Results:

  • Univariate analyses revealed significant associations between trait aggression and childhood maltreatment, post-traumatic stress disorder, substance abuse, antisocial personality disorder, borderline personality disorder, and current mood symptoms (depression and mania).
  • Stepwise multiple regression identified comorbid borderline personality disorder, depressive symptoms, and manic symptoms as significant predictors of trait aggression in the BD sample.
  • These predictors remained significant even after controlling for other potential confounding factors.

Conclusions:

  • Comorbid borderline personality disorder and current mood state (manic and depressive symptoms) are significant independent predictors of trait aggression in individuals with bipolar disorder.
  • The findings suggest a need to refine diagnostic criteria and consider the interplay between bipolar disorder and borderline personality disorder in understanding aggression.
  • These results have implications for the developmental pathways contributing to aggression in patients with comorbid personality disorders and bipolar disorder.