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Related Experiment Video

Updated: Jul 7, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

Left atrial appendage exclusion using an Amplatzer device.

Ignacio Cruz-Gonzalez, Roberto J Cubeddu, Maria Sanchez-Ledesma

    International Journal of Cardiology
    |February 15, 2008
    PubMed
    Summary

    Patients with atrial fibrillation (AF) face higher stroke risks, often from clots in the left atrial appendage (LAA). Percutaneous LAA exclusion offers a stroke prevention alternative for high-risk patients unsuitable for anticoagulation.

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    Transseptal Puncture for Left Atrial Appendage Closure: A Consensus Document From the Second European Left Atrial Appendage Club.

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    Area of Science:

    • Cardiology
    • Interventional Cardiology
    • Medical Devices

    Background:

    • Atrial fibrillation (AF) significantly increases cardioembolic stroke risk.
    • Thrombi causing ischemic events commonly originate in the left atrial appendage (LAA).
    • Percutaneous LAA exclusion is an emerging stroke prevention strategy for AF patients with contraindications to oral anticoagulants.

    Observation:

    • The Amplatzer septal occluder, not initially designed for LAA occlusion, has been successfully utilized.
    • A case study details the successful percutaneous exclusion of the LAA using an Amplatzer septal occluder in an AF patient.

    Findings:

    • The Amplatzer septal occluder demonstrated successful LAA exclusion in the presented case.
    • This approach offers a viable alternative to surgical closure and long-term oral anticoagulation.

    More Related Videos

    The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
    23:33

    The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

    Published on: February 28, 2012

    Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
    07:39

    Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

    Published on: August 16, 2021

    Related Experiment Videos

    Last Updated: Jul 7, 2026

    Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
    28:13

    Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

    Published on: February 26, 2013

    The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
    23:33

    The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

    Published on: February 28, 2012

    Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
    07:39

    Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

    Published on: August 16, 2021

    Implications:

    • Percutaneous LAA exclusion using the Amplatzer septal occluder shows promise for stroke prevention in specific patient populations.
    • Further clinical trials are warranted to validate the long-term efficacy and safety of this device for LAA occlusion.