Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jul 7, 2026

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

Published on: January 7, 2019

Fiber-optic sensor system for rapid positioning of a microelectrode array.

P G Lopresti, W E Finn

|February 15, 2008

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Observation of optical limiting and backscattering of nanosecond laser pulses in liquid-crystal fibers.

Optics letters·2009

Same author

The paper-case clinic: teaching medical physiology by PBL.

Academic medicine : journal of the Association of American Medical Colleges·1996

Same author

Ethical dilemmas imposed by the Medicare hospice regulations.

New York state journal of medicine·1987

Same author

Hospice at the crossroads: the physician director.

The American journal of hospice care·1987

Same author

A model for studying a viscerosomatic reflex induced by myocardial infarction in the cat.

The Journal of the American Osteopathic Association·1978

Same author

The olfactory and auditory mediated sex attraction in Achroia grisella (Fabr.).

Die Naturwissenschaften·1971

Same journal

Multifunctional reconfigurable terahertz metasurface based on vanadium dioxide phase transition: achieving broadband absorption and efficient polarization conversion.

Applied optics·2026

Same journal

High-Q-factor electromagnetically induced transparency utilizing quasi-bound states in the continuum in an all-dielectric terahertz metasurface.

Applied optics·2026

Same journal

Automated stitching interferometry for high-precision metrology of X-ray mirrors.

Applied optics·2026

Same journal

Experimental demonstration of an approach to designing a metal-dielectric DBR resonant cavity structure.

Applied optics·2026

Same journal

High-precision wavefront reconstruction from a single-shot interferogram using a physics-driven hybrid feature calibration network.

Applied optics·2026

Same journal

Ultra-high-Q Fano resonance based on coupled topological corner states in Kagome photonic crystals.

Applied optics·2026

See all related articles

A new fiber-optic sensor precisely positions microelectrode arrays above frog retinas. This innovation aids in studying neural responses and may be adapted for other positioning tasks.

Area of Science:

Biomedical Engineering
Neuroscience
Optics

Background:

Accurate positioning of microelectrode arrays is crucial for studying neural activity in vivo.
Existing methods for retinal positioning can be imprecise, limiting experimental resolution.
The development of novel sensing technologies is needed to enhance precision in neurophysiological research.

Purpose of the Study:

To develop and evaluate a fiber-optic intensity sensor for precise vertical positioning of microelectrode arrays above a live frog retina.
To assess the sensor's performance with different fiber configurations and reflector types.
To explore the sensor's potential applications in neurostimulation and other positioning tasks.

Main Methods:

Development of a fiber-optic intensity sensor using closely spaced fibers for illumination and reflection collection.

More Related Videos

Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording

Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording

Published on: September 1, 2022

Open-source Toolkit: Benchtop Carbon Fiber Microelectrode Array for Nerve Recording

Open-source Toolkit: Benchtop Carbon Fiber Microelectrode Array for Nerve Recording

Published on: October 29, 2021

Related Experiment Videos

Last Updated: Jul 7, 2026

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response

Published on: January 7, 2019

Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording

Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording

Published on: September 1, 2022

Open-source Toolkit: Benchtop Carbon Fiber Microelectrode Array for Nerve Recording

Open-source Toolkit: Benchtop Carbon Fiber Microelectrode Array for Nerve Recording

Published on: October 29, 2021

Electronic processing of the optical signal to control an automated positioning circuit.

Experimental and theoretical evaluation of fiber types and separation for specular and diffuse reflectors, both in vitro and in vivo.

Main Results:

Multimode fibers on 125-micrometer centers were selected for retinal experimentation.
The sensor demonstrated effective vertical positioning capabilities.
The system's performance was validated through in vitro and in vivo tests.

Conclusions:

The developed fiber-optic intensity sensor enables precise vertical positioning of microelectrode arrays for retinal research.
The sensor has significant applications in assessing the spatial selectivity of multielectrode array stimulation.
The technology shows promise for adaptation to lateral positioning tasks in biological and optical systems.