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Published on: February 22, 2018
[How do Argentinean psychiatrists treat depression?]
Eduardo A Leiderman1, Martín Nemirovsky, Irene Elenitza
11ra Cátedra de Farmacología, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155, Piso 15, CP 1113, Buenos Aires, Argentina. edule@psi.uba.ar
Argentinean psychiatrists widely use antidepressants for major depression, with common choices like paroxetine and sertraline. However, prescribing practices showed discrepancies compared to established treatment guidelines.
Area of Science:
- Psychiatry
- Pharmacology
Context:
- Major depression treatment in Argentina.
- Survey of 402 psychiatrists in October 2005.
Purpose:
- To analyze Argentinean psychiatrists' prescribing habits for major depression.
- Compare these practices with existing treatment guidelines.
Summary:
- 88.2% of psychiatrists believe all depressed patients require medication.
- Paroxetine, sertraline, and fluoxetine were most prescribed for outpatients; venlafaxine for inpatients.
- Most favored 12-24 month antidepressant therapy post-remission, with stable dosages.
- Dual antidepressants and SSRIs were the most common combination.
- Augmentation strategies primarily involved adding other antidepressants, with limited use of lithium or thyroid hormones.
- Prescribing patterns varied based on physician-specific factors.
Impact:
- Reveals significant differences between clinical practice and evidence-based guidelines for major depression treatment.
- Highlights the need for further investigation into the reasons behind these discrepancies.
- Suggests developing strategies to bridge the gap between practice and guidelines for improved patient outcomes.
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