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Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
Published on: August 9, 2012
[Continous bladder irrigation with amikacin as adjuvant treatment for emphysematous cystitis]
Jeff R Cortés González1, Gerardo E Ortiz Lara, Jorge A Arratia Maqueo
1Servicio de Urología, Hospital Universitario Dr. José E. González, UANL, Monterrey, México. jrcor77@yahoo.com
Objective:
To demonstrate that continuos intravesical irrigation with amikacin is an effective adyuvant treatment in Emphisematous Cistitis therapy.
Methods:
A 3 way transurethral Foley catheter was placed and a continuous intravesical irrigation was initiated with amikacin 500 mg in 1L of normal saline (500 micrograms per ml) within 6 hours 4 times a day and three consecutive days.
Results:
After 3 days of treatment the patient showed significant clinical response. A new CT scan showed the absence of gas in the bladder wall compared to the previews CT and negative urine culture was obtained.
Conclusions:
We established that treatment using adjuvant continuous intravesical irrigation with amikacin can reduce hospital stay and accelerate the patient's healing process, as well as an earlier negativisation of urine cultures. A comparative prospective study is needed to evaluate if in fact this treatment variant produces a real benefit compared to conventional therapy.
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