[Protective properties of the immunomodulator Gala-Vet in a complex with cellular Echinococcus multilocularis antigen...

The paper provides the results of studying the protective properties of the immunomodulator Gala-Vet alone and in combination with the cellular antigens of Echinococcus multiocularis protoscolexes in experimental murine hydatidosis. After checking inoculation with E. multilocularis protoscolexes and acephalocysts (a dose being 750+/-50 specimens), the protective efficiency in the mice immunized with the cellular antigen subcutaneously injected thrice in a dose of 60 micromg was 91.7%. In the mice immunized with the cellular antigen of parasitic protoscolexes in the same dose in the same manner, the protective effect was 75%. The similar protective effect (75%) was recorded in the group of mice receiving the immunomodulator Gala-Vet alone. After inoculation and slaughter, all the control mice administered a sterile physiological solution in the immunization period were infested.