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Altered fever response in end stage renal disease: implications for critical care nurses
Rhonda Matheson1, Jo-Ann V Sawatzky
1Medical Intensive Care Unit, St. Boniface Hospital, Winnipeg, Manitoba. Ronnie_from_canada@yahoo.com
Abstract:
Patients with compromised renal function are more likely to suffer from infections and fever than the general population. Because these patients often have an altered fever response, the assessment and management of this response to infection can be particularly challenging for critical care nurses. In this article, the authors use a nursing framework to examine the phenomenon of fever in critically ill patients with end stage renal disease. Implications for nursing practice, education, and research are explored.
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Renal Failure: Dose Adjustments
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...