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Local tissue reaction to intravenous fluorouracil and leucovorin
G S Umstead1, N L Fryer, D A Decker
1Department of Pharmaceutical Services, William Beaumont Hospital, Royal Oak, MI 48073.
DICP : the Annals of Pharmacotherapy
|March 1, 1991
Abstract:
Fluorouracil alone can cause a variety of dermatologic adverse effects; however, it is not considered to be a chemical vesicant. We report a case of apparent enhanced local skin reaction from the combination of intravenous fluorouracil and leucovorin. The reaction occurred in the patient's other hand on rechallenge.