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[Quantification of ventricular mass and function using real-time free-breathing SSFP sequences].

G Bastarrika Alemañ¹, P D Domínguez Echávarri, P M Azcárate Agüero

¹Servicio de Radiología. Clínica Universitaria. Universidad de Navarra. Pamplona. España. bastarrika@unav.es

|February 16, 2008

Summary

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Real-time free-breathing steady-state free precession (SSFP) MRI accurately quantifies ventricular mass and function, showing excellent correlation with conventional breath-hold SSFP. This technique offers reproducible cardiac parameter assessment without requiring patients to hold their breath.

Area of Science:

Cardiovascular Imaging
Magnetic Resonance Imaging (MRI)
Cardiac Physiology

Context:

Conventional breath-hold segmented steady-state free precession (SSFP) sequences are standard for cardiac MRI but can be challenging for patients.
Assessing ventricular mass and function is crucial for diagnosing and managing cardiopathies.
Real-time imaging offers a potential alternative to breath-hold techniques.

Purpose:

To compare the accuracy of real-time free-breathing SSFP sequences against conventional breath-hold SSFP sequences for quantifying ventricular mass and function.
To evaluate the correlation and reproducibility of cardiac parameter measurements between the two SSFP techniques.

Summary:

Cardiac MRI was performed on 15 patients using both conventional breath-hold and real-time free-breathing SSFP sequences.

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Measurements included left ventricular mass (LVM), and systolic (VTS) and diastolic (VTD) volumes, and ejection fraction (EF) for both ventricles.

An excellent correlation (r=0.9) was found between real-time free-breathing and breath-hold SSFP for all assessed cardiac parameters, including LVM, with minimal mean differences.

Impact:

Real-time free-breathing SSFP MRI provides a reliable and reproducible method for precise quantification of ventricular mass and function.
This technique eliminates the need for breath-holding, potentially improving patient comfort and scan efficiency in cardiac MRI.
The findings support the clinical utility of free-breathing SSFP for accurate cardiac assessment in patients with cardiopathies.