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Immunodominant-peptide recognition: beta testing TCRalphabeta

Jia-huai Wang1, Robert J Mallis, Ellis L Reinherz

  • 1Laboratory of Immunobiology and Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney St., Boston, MA 02115, USA.

Immunity
|February 16, 2008
PubMed

In this issue, Ishizuka et al. (2008) define human T cell-receptor recognition of an immunodominant influenza A matrix peptide bound to human leukocyte antigen HLA-A*0201 in atomic detail, raising provocative questions about beta chain function.

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