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Burkitt's lymphoma: a model for clinical oncology
E Bouffet1, D Frappaz, R Pinkerton
1Pediatric Oncology Department, Centre Léon Bérard, Lyon.
European Journal of Cancer (Oxford, England : 1990)
|January 1, 1991
Abstract:
Burkitt's lymphoma, a pathological entity initially described in Africa, is the most common childhood lymphoma in western countries and represents approximately 5% of all adults lymphomas. This high grade small non-cleaved diffuse lymphoma is a model with which to study the relations between cancer and viruses, the chromosomes and the genes. Burkitt's lymphoma is also a model for clinical research which allows evaluation of the dose effect concept with chemotherapy and the role of megatherapy with autologous bone marrow rescue.