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Published on: May 2, 2025
Complementary medicines in pediatric bipolar disorder.
S Bogarapu1, J R Bishop, C D Krueger
1Department of Psychiatry, Center for Cognitive Medicine, University of Illinois at Chicago, College of Medicine, Chicago, IL 60612, USA.
Complementary and alternative medicines (CAM) are increasingly used for pediatric bipolar disorder. While some CAM like Omega-3s show promise as adjunctive treatments, conventional medicine remains the primary choice.
Area of Science:
- Psychiatry
- Pediatric Mental Health
- Complementary and Alternative Medicine (CAM)
Background:
- Growing use of CAM for mental health conditions, especially in children.
- Challenges in pediatric mental illness treatment drive interest in alternatives.
- Increased CAM utilization in psychiatry for difficult-to-treat conditions like pediatric bipolar disorder (BD).
Purpose of the Study:
- To review studies on the utility of CAM in bipolar disorder patients.
- To inform healthcare providers about CAM use in pediatric patients.
- To assess the efficacy and role of CAM in managing pediatric bipolar disorder.
Main Methods:
- Literature review of studies investigating CAM in bipolar patients.
- Selection of relevant studies for analysis.
- Synthesis of findings on specific CAM interventions.
Main Results:
- Omega-3 fatty acids and lecithin/choline show preliminary potential for bipolar disorder treatment.
- S-adenosyl methionine (SAM-e) and inositol have data supporting efficacy in depressive symptoms.
- CAM may serve as useful adjunctive treatments, but limited data supports standalone therapy.
Conclusions:
- Conventional medicines remain the first-line treatment for pediatric bipolar disorder.
- Healthcare providers must inquire about and understand the risks and benefits of CAM in children.
- Further research is needed to establish the role of CAM as standalone therapy.
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