Related Experiment Video
Updated: Jul 7, 2026
Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
Chromosomal changes induced in mouse bone marrow cells following six weeks inhalation of cyclohexanol
Katarína Siviková1, J Dianovský, Elena Piesová
1Institute of Genetics, University of Veterinary Medicine, Komenského 73, 041 81 Kosice, Slovak Republic. sivikova@uvm.sk
Abstract:
The effects of low doses of cyclohexanol exposure were studied in mouse bone marrow cells including chromosome aberrations (CA), micronucleus (MN) and sister chromatid exchanges (SCE) as biomarkers. Capillaries with a tested agent that was evaporated continuously were placed in an experimental chamber for six weeks. No clastogenic and/or aneugenic effect of CA and MN induction was observed. A significant elevation of induced damage was achieved in the SCE study (p < 0.001) that has confirmed the early exposure of cyclohexanol to mice.
