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Intussusception in children in Southern Israel: disparity between 2 populations

David Greenberg1, Noga Givon-Lavi, Nitza Newman

  • 1The Pediatric Infectious Disease Unit, Soroka University Medical Center, the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. dudi@bgu.ac.il

The Pediatric Infectious Disease Journal
|February 19, 2008
PubMed

Insights

Intussusception rates were high in Southern Israel before rotavirus vaccines, particularly in Jewish infants. Bedouin infants showed a significant increase in intussusception during the study period.

Area of Science:

  • Pediatric gastroenterology
  • Vaccine-preventable diseases
  • Public health surveillance

Background:

  • Intussusception is a serious intestinal condition that has been linked to a specific rotavirus vaccine.
  • Understanding pre-vaccine incidence is crucial for assessing vaccine impact and public health strategies.

Purpose of the Study:

  • To determine the incidence rates of intussusception in children under 5 years old in Southern Israel.
  • To analyze trends and demographic differences in intussusception before the introduction of newer rotavirus vaccines.

Main Methods:

  • A retrospective population-based study was conducted using data from Soroka Medical Center.
  • Included all children under 5 admitted with intussusception (ICD-9 code) between 1990 and 2004.
  • Data analyzed for Jewish and Bedouin populations, comparing incidence rates, seasonality, and co-occurring conditions.

Main Results:

  • 316 intussusception cases were recorded; 76% in Jewish children, 24% in Bedouin children.
  • Mean annual rates per 100,000 children under 5 were significantly higher in Jewish (49.3) vs. Bedouin (18.9) children.
  • Bedouin children showed a significant increase in intussusception rates over the study period and a seasonal pattern (March-May).

Conclusions:

  • Pre-vaccine intussusception incidence was notably high, especially among Jewish infants in Southern Israel.
  • A significant rise in intussusception rates was observed in Bedouin infants during the 1990-2004 period.
  • Findings highlight the importance of ongoing surveillance for intussusception, particularly in diverse populations.
Abstract

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