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Updated: Jul 7, 2026

Artificial Intelligence Approaches to Assessing Primary Cilia
Published on: May 1, 2021
Ciliogenesis, ciliary function, and selective isolation
1Department of Physiology and Biophysics, Boston University School of Medicine, Boston, Massachusetts 02118, USA. rstephen@bu.edu
Abstract:
In addition to their classic role in cell motility, certain cilia have sensory or signaling functions. In sea urchin embryos, short motile cilia randomly propel the early embryo, while a group of long, immotile cilia appear later, coincident with directional swimming and localized within a region that gives rise to the larval nervous system. Motile cilia can be selectively removed by treatment with a novel derivative of dillapiol, leaving the putative sensory cilia for comparative investigation and a gently deciliated embryo ready for studies of regeneration signaling.
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