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Updated: Jul 7, 2026
07:10
Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
Published on: August 24, 2019
Cognitive training is ineffective in hypoxemic COPD: a six-month randomized controlled trial
Raffaele Antonelli Incalzi1, Andrea Corsonello, Luigi Trojano
1Geriatric Medicine, University Campus Bio-Medico, Rome, Italy.
Rejuvenation Research
|February 19, 2008
Summary
Cognitive training did not significantly improve cognitive function in patients with chronic obstructive pulmonary disease (COPD) and hypoxemia. A comprehensive care approach may help slow cognitive decline in these patients.
Area of Science:
- Neurology
- Pulmonology
- Psychology
Background:
- Cognitive impairment is common in chronic obstructive pulmonary disease (COPD) patients with hypoxemia.
- The impact of cognitive training on cognition in hypoxemic COPD patients remains uninvestigated.
Purpose of the Study:
- To determine if cognitive training can preserve cognitive function in patients with hypoxemic COPD.
- To evaluate the efficacy of cognitive interventions in this population.
Main Methods:
- 105 COPD patients with hypoxemia were randomized into two groups: standardized multidimensional care with cognitive training or without.
- Cognitive function was assessed at baseline and at 1.5, 4, and 6 months using the Mini Mental State Examination (MMSE) and the Mental Deterioration Battery (MDB).
- Statistical analysis involved repeated measures ANOVA to compare cognitive changes between groups.
Main Results:
- Neither the cognitive training group nor the control group showed significant improvements in overall cognitive performance.
- A slight trend towards improvement in verbal fluency and verbal memory was observed in both groups.
- Cognitive intervention demonstrated no significant effect on cognitive performance in hypoxemic COPD patients.
Conclusions:
- Cognitive training appears ineffective for improving or preserving cognitive function in patients with COPD and hypoxemia.
- A standardized, multidimensional therapeutic approach, encompassing various aspects of COPD care, may play a role in mitigating cognitive decline.
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