Related Experiment Video
Updated: Jul 7, 2026
07:25
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Therapies in development for castrate-resistant prostate cancer
Andrea L Harzstark1, Charles J Ryan
1Department of Medicine, University of California, San Francisco, 1600 Divisadero Street, Box 1711, San Francisco, CA 94115, USA. andrea.harzstark@ucsf.edu
Expert Review of Anticancer Therapy
|February 19, 2008
Summary
Active treatments for advanced prostate cancer are limited, necessitating research into new therapies. This review covers promising novel agents and combination treatments, including androgen-targeting drugs, chemotherapies, and immunotherapies.
Area of Science:
- Oncology
- Medical Research
Background:
- Advanced prostate cancer lacks sufficient effective medical treatments.
- There is a critical need for novel therapeutic strategies.
Purpose of the Study:
- To review emerging medical therapies for advanced prostate cancer.
- To highlight the potential and challenges of new treatment approaches.
Main Methods:
- Review of current clinical research and evaluated treatments.
- Analysis of therapies targeting adrenal androgens, novel chemotherapies, and immunotherapeutics.
Main Results:
- Multiple new treatments are under investigation, showing promise.
- Evaluated therapies include abiraterone, satraplatin, ixabepilone, bevacizumab, calcitriol, sipuleucel-T, GVAX, and ipilimumab.
Conclusions:
- Emerging therapies offer new hope for advanced prostate cancer patients.
- Further research is essential to overcome development challenges and optimize treatment efficacy.
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