Related Experiment Video

Updated: Jul 7, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
07:54

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

Current concepts in malignant pleural mesothelioma

Andrew J Kaufman1, Harvey I Pass

  • 1New York University Medical Center, Department of Surgery, 550 First Avenue, NBV-15N1, New York, NY 10016, USA. kaufma01@med.nyu.edu

Expert Review of Anticancer Therapy
|February 19, 2008
PubMed

Insights

Malignant pleural mesothelioma (MPM) is a deadly cancer linked to asbestos. Research into MPM

Area of Science:

  • Oncology
  • Pathology

Background:

  • Malignant pleural mesothelioma (MPM) is a rare, lethal cancer.
  • Asbestos exposure is the primary cause of MPM.
  • MPM incidence is projected to rise globally over the next two decades.

Purpose of the Study:

  • To explore novel diagnostic, preventative, and therapeutic strategies for MPM.
  • To advance understanding of MPM pathogenesis through molecular and genetic profiling.

Main Methods:

  • Molecular and genetic profiling of MPM tumors and patients.
  • Review of current and potential treatment strategies.

Main Results:

  • Limited treatment options currently exist for MPM with no established consensus.
  • Multimodality therapy (surgery, chemotherapy, radiation) offers the best survival chance for select patients.

Conclusions:

  • Further research into MPM pathogenesis is crucial for developing new treatments.
  • Multimodality therapy is the current best approach for eligible MPM patients.

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Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model09:31

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