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Developmental characteristics of very low-birthweight infants at 18 months' corrected age according to birthweight

Yumi Kono1, Jun Mishina, Noriko Sato

  • 1Maternal and Perinatal Center, School of Medicine, Tokyo Women's Medical University, Tokyo, Japan. ykono@boshi.twmu.ac.jp

Pediatrics International : Official Journal of the Japan Pediatric Society
|February 19, 2008
PubMed

Insights

Developmental outcomes for very low-birthweight (VLBW) infants vary by birth weight. Infants born under 750g showed distinct developmental challenges compared to other VLBW infants at 18 months corrected age.

Area of Science:

  • Neonatal development
  • Pediatric neurology
  • Developmental pediatrics

Background:

  • Very low-birthweight (VLBW) infants often exhibit varied developmental trajectories.
  • Infants with extremely low birthweight (<750 g) may present unique developmental profiles.
  • Understanding these differences is crucial for targeted interventions.

Purpose of the Study:

  • To delineate developmental profiles of very low-birthweight (VLBW) infants.
  • To compare developmental outcomes based on birthweight stratification.
  • To investigate potential differences in infants with birthweight <750 g.

Main Methods:

  • A cohort of 564 VLBW infants without neurological impairment was followed.
  • Developmental assessments were conducted at 18 months corrected age using the Kyoto Scale of Psychological Development (KSPD).
  • Infants were categorized into four groups based on 250 g birthweight intervals for outcome comparison.

Main Results:

  • Extremely low-birthweight infants (<750 g) demonstrated more fine motor clumsiness.
  • These infants had reduced expressive language (meaningful words) despite intact receptive language.
  • Significantly lower developmental quotients (DQ) and increased hyperactivity were observed in the <750 g group.

Conclusions:

  • Developmental profiles of VLBW infants correlate significantly with birthweight.
  • Birthweight is a critical factor influencing neurodevelopmental outcomes at 18 months corrected age.
  • These findings offer valuable insights for managing VLBW infant development.
Abstract

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