Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

Mitral Valve Prolapse III: Nursing Management

Mitral Valve Prolapse III: Nursing Management

The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...

Mitral Valve Prolapse I: Introduction

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...

Mitral Valve Prolapse II: Assessment and Management

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular tachycardia.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dual Mobility versus Conventional Total Hip Arthroplasty for Femoral Neck Fractures: A Multicenter Propensity-Matched Study on Dislocation Risk.

The Journal of arthroplasty·2026

Same author

A safe technique in performing gluteus maximus tenotomy in the Kocher-Langenbeck approach.

Hip international : the journal of clinical and experimental research on hip pathology and therapy·2025

Same author

Intra-articular Vancomycin Reduces Prosthetic Infection in Primary Hip and Knee Arthroplasty-Response to Queries.

Arthroplasty today·2024

Same author

Intra-articular Vancomycin Reduces Prosthetic Infection in Primary Hip and Knee Arthroplasty.

Arthroplasty today·2024

Same author

A Five-Month-Old Boy With Hypotonia, Electrolyte Derangements, and Failure to Thrive.

Cureus·2023

Same author

Identification of cognitive impairment, depression, and fatigue among multiple sclerosis patients in a large comprehensive care center: A mixed-methods, qualitative study.

Multiple sclerosis and related disorders·2022

Search research articles

Related Experiment Video

Updated: Jul 7, 2026

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice

Published on: May 23, 2025

Ventricular metastasis without atrial or caval involvement: a rare presentation.

Ruby Satpathy¹, Joseph Lynch, Syed M Mohiuddin

¹Department of Cardiology, Creighton University School of Medicine, Omaha, Nebraska 68131, USA. ruby.satpathy@cardiac.creighton.edu

Echocardiography (Mount Kisco, N.Y.)

|February 19, 2008

Summary

Metastases to the heart ventricles from renal cell carcinoma are rare. This case shows successful treatment of cardiac metastases with systemic therapy, leading to tumor reduction without surgery.

More Related Videos

A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer

A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer

Published on: December 26, 2016

Related Experiment Videos

Last Updated: Jul 7, 2026

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice

Published on: May 23, 2025

A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer

A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer

Published on: December 26, 2016

Area of Science:

Cardiology
Oncology
Pathology

Background:

Right ventricular metastases from renal cell carcinoma (RCC) are uncommon, especially without inferior vena cava (IVC) or right atrial involvement.
Early detection and management are crucial for improving patient outcomes in metastatic RCC.

Observation:

A 44-year-old male presented with a thigh mass, later diagnosed as epithelial sarcoma or metastasis.
Cardiac evaluation revealed masses in the right and left ventricles, confirmed by transesophageal echocardiogram.
CT scan identified a right renal mass and ventricular masses, with no IVC or atrial involvement.

Findings:

The patient underwent radical nephrectomy and systemic chemotherapy with interleukin-2 for metastatic RCC.
Follow-up echocardiograms demonstrated a significant reduction in cardiac metastasis size.
Tumor regression was achieved without surgical resection of the ventricular masses.

Implications:

This case highlights a rare presentation of asymptomatic ventricular metastases from RCC.
Systemic therapy can be effective in managing cardiac metastases from RCC.
The findings offer new insights into the treatment of cardiac involvement in metastatic renal cell carcinoma.