Options for screening colonoscopy without sedation: sequel to a pilot study in U.S. veterans
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Updated: Jul 7, 2026

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
Felix W Leung1, Surinder K Mann, Rodelei Salera
1Division of Gastroenterology, Medical and Research Services, Sepulveda Ambulatory Care Center, Veterans Affairs Greater Los Angeles Healthcare System and David Geffen School of Medicine at University of California, Los Angeles, California, USA.
Background:
Sedation on demand combined with a novel water infusion technique enabled 23 of 44 veterans to complete screening colonoscopy without sedation.
Objective:
With use of the usual air insufflation technique, we determined the proportion of patients who could complete colonoscopy without sedation.
Design:
Retrospective review of prospectively collected data in a performance improvement project to minimize the burden of sedation.
Setting:
A Veterans Affairs open access screening colonoscopy program.
Subjects:
Ninety-three consecutive veterans who accepted on-demand sedation or scheduled no sedation.
Method:
Usual air insufflation during colonoscope insertion. Medications were administered at the veteran's request.
Results:
Twenty-three veterans chose scheduled unsedated colonoscopy; 22 were completed without sedation. Sedation on demand enabled 54 to complete the procedure without medications; 16 requested medications to complete colonoscopy. Nurses' expectations indicated that the choices were credible options.
Conclusions:
Options for screening colonoscopy without sedation combined with usual air insufflation are feasible among U.S. veterans. Confirmation by randomized controlled trial and evaluation of the impact on institutional costs and patient adherence to screening and surveillance colonoscopy deserve to be considered.
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