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Bacterial Gastroenteritis

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Related Experiment Video

Updated: Jul 7, 2026

In Vitro Apical-Out Enteroid Model of Necrotizing Enterocolitis
09:11

In Vitro Apical-Out Enteroid Model of Necrotizing Enterocolitis

Published on: June 8, 2022

Necrotizing enterocolitis.

Pinchi S Srinivasan1, Michael D Brandler, Antoni D'Souza

  • 1Division of Neonatology, Department of Pediatrics, New York Hospital Queens, Affiliate Weill Medical College of Cornell University, 56-45, Main Street, Flushing, NY 11355, USA. pns9001@nyp.org

Clinics in Perinatology
|February 19, 2008
PubMed
Summary

Necrotizing enterocolitis (NEC) causes bowel injury and necrosis, potentially leading to sepsis and death. This review covers NEC causes, development, and prevention strategies.

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Last Updated: Jul 7, 2026

In Vitro Apical-Out Enteroid Model of Necrotizing Enterocolitis
09:11

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Published on: June 8, 2022

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
05:39

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Published on: November 30, 2021

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome
06:51

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome

Published on: July 28, 2023

Area of Science:

  • Neonatal medicine
  • Gastroenterology
  • Pediatric surgery

Background:

  • Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease in neonates.
  • It involves bowel injury, intramural air, and potential necrosis with perforation.
  • NEC progression can result in sepsis and mortality despite early treatment.

Purpose of the Study:

  • To review current scientific knowledge on the etiology and pathogenesis of NEC.
  • To discuss potential preventive measures for NEC.

Main Methods:

  • Literature review of scientific knowledge on NEC.
  • Analysis of etiological and pathogenetic factors.
  • Exploration of preventive strategies.

Main Results:

  • NEC pathogenesis involves complex interactions leading to bowel injury.
  • Risk factors and mechanisms contributing to NEC development are detailed.
  • Potential preventive strategies are discussed based on current research.

Conclusions:

  • Understanding NEC etiology and pathogenesis is crucial for effective prevention.
  • Further research into preventive measures may reduce NEC incidence and improve outcomes.
  • Aggressive management is necessary, but prevention remains a key goal.