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Related Concept Videos

Fats as Energy Storage Molecules01:06

Fats as Energy Storage Molecules

Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis directly...
Fats as Energy Storage Molecules01:06

Fats as Energy Storage Molecules

Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis directly...
Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Lipids: Dietary Sources and Requirements01:18

Lipids: Dietary Sources and Requirements

Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ meats, shellfish,...

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Related Experiment Video

Updated: Jul 7, 2026

Fat-Water Phantoms for Magnetic Resonance Imaging Validation: A Flexible and Scalable Protocol
07:59

Fat-Water Phantoms for Magnetic Resonance Imaging Validation: A Flexible and Scalable Protocol

Published on: September 7, 2018

The reliability of fat.

T Meyer1, C Folz, F Rosenberger

  • 1Institute of Sports and Preventive Medicine, University of Saarland, Saarbrücken, Germany. tim.meyer@uni-paderborn.de

Scandinavian Journal of Medicine & Science in Sports
|February 20, 2008
PubMed
Summary
This summary is machine-generated.

Maximal fat oxidation (Fat(max)) determination lacks reproducibility for training prescription. Intraindividual variability is too large, suggesting this parameter is unreliable for guiding exercise intensity.

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Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans
10:29

Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans

Published on: June 4, 2014

Area of Science:

  • Exercise Physiology
  • Metabolic Research
  • Sports Science

Background:

  • Maximal fat oxidation (Fat(max)) is a key parameter for optimizing exercise intensity for fat metabolism.
  • Incremental exercise tests are commonly used to determine Fat(max).
  • The reproducibility of Fat(max) measurements has not been sufficiently investigated.

Purpose of the Study:

  • To assess the reproducibility of determining maximal fat oxidation (Fat(max)) during incremental exercise.
  • To evaluate the intraindividual variability of Fat(max) in healthy subjects.
  • To determine if Fat(max) is a reliable parameter for prescribing training intensity.

Main Methods:

  • Twenty-one healthy participants completed two identical incremental cycling tests to determine Fat(max).
  • Tests involved five 6-minute stages, with intensity based on blood lactate and respiratory exchange ratio.
  • Measurements included oxygen consumption (VO(2)) and fat oxidation rates (VO(2Fat)).

Main Results:

  • No significant differences were found between the two Fat(max) determinations (P > 0.20).
  • Strong linear correlations were observed between tests for total VO(2) (r=0.84) and VO(2Fat) (r=0.83).
  • However, Bland-Altman analysis revealed wide 95% limits of agreement, indicating substantial intraindividual variability.

Conclusions:

  • Spontaneous intraindividual variability in Fat(max) is considerable.
  • The current methods for determining Fat(max) show insufficient reproducibility.
  • Fat(max) is not recommended for the prescription of training intensity due to its variability.