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Published on: September 5, 2017
Epidemiological trends of childhood tuberculosis in Taiwan, 1998-2005
1Department of Internal Medicine, Branch for Disease Control and Prevention, Taipei City Hospital, Taipei, Taiwan. pdw@ms34.hinet.net
Insights
Tuberculosis (TB) incidence rose in children and adults in Taipei City. Addressing adult TB cases is key to reducing childhood TB exposure and improving overall TB control.
Area of Science:
- Epidemiology
- Pediatrics
- Public Health
Background:
- Understanding childhood tuberculosis (TB) epidemiology is vital for effective TB control strategies.
- Childhood TB presents unique challenges in diagnosis and management.
Purpose of the Study:
- To analyze trends and characteristics of TB in children (0-14 years) in Taipei City, Taiwan.
- To inform public health interventions for pediatric TB.
Main Methods:
- Retrospective analysis of childhood TB cases (1998-2005) from the National Tuberculosis Registry Database in Taipei City.
- Examination of epidemiological and clinical data, including age-specific incidence and TB site distribution.
Main Results:
- TB incidence rates increased significantly in children aged 0-14 years and adults during 1998-2005.
- Extra-pulmonary TB accounted for 31.9% of cases, with lymph node, bone/joint, and pleural sites being most common.
- Age-specific incidence peaked in 10-14 year olds, while extra-pulmonary TB was more prevalent in younger children (0-4 years).
Conclusions:
- The rise in childhood TB incidence may correlate with increased adult TB rates.
- Targeting and treating infectious adult TB cases is crucial to minimize pediatric TB transmission.
- Public health efforts should focus on identifying and treating adult sources of infection to protect children.
Setting:
Understanding tuberculosis (TB) epidemiology among children is critical to overall TB control.
Objective:
To investigate the trends and epidemiological and clinical characteristics of TB in children aged 0-14 years in Taipei City, Taiwan.
Design:
Data on all childhood TB cases in Taipei City from 1998 to 2005 were obtained from the National Tuberculosis Registry Database.
Results:
TB incidence rates increased significantly in both adults and children aged 0-14 years during the study period. The age-specific rate in children was highest in 10-14-year-olds and lowest in the 5-9 years age group. Of the 163 childhood TB cases, 52 cases (31.9%) were extra-pulmonary, with the highest proportional rate, of 39.6%, in the 0- 4 years age group. The most common site of extra-pulmonary involvement was the lymph nodes, followed by the bones and joints and the pleura. Bone and joint involvement occurred significantly more often in children aged 0- 4 years, while pleural disease was significantly more frequent in children aged 10-14 years. Only two cases of TB meningitis were identified.
Conclusions:
The increase in childhood TB may be associated with the increase in the incidence of the disease in adults. Identifying and treating infectious sources, usually adults, can reduce the risk of TB exposure in children.
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