Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gross Anatomy of the Lungs01:17

Gross Anatomy of the Lungs

The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pleura of the Lungs01:13

Pleura of the Lungs

The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
Pulmonary Edema II: Pathophysiology01:18

Pulmonary Edema II: Pathophysiology

Pulmonary edema is the accumulation of fluid in the interstitial and alveolar spaces of the lungs, impairing gas exchange and oxygen delivery. It may be cardiogenic or noncardiogenic, but both reduce oxygenation and lung compliance.Cardiogenic Pulmonary EdemaCardiogenic edema results from increased hydrostatic pressure in pulmonary capillaries, usually due to left ventricular dysfunction from myocardial infarction, heart failure, or valvular disease. Ineffective cardiac pumping causes blood to...
Atelectasis II: Pathophysiology01:10

Atelectasis II: Pathophysiology

Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preoperative Left Atrial Strain Reservoir and the Risk of Postoperative Atrial Fibrillation After Major Lung Resection: A Prospective Single-Center Study.

Journal of cardiothoracic and vascular anesthesia·2026
Same author

DOT1L activity limits transcription elongation velocity and favors RNAPII pausing to facilitate mutagenesis by AID.

Nature communications·2026
Same author

Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10.

Cell reports·2025
Same author

Polyglycolic Acid Aerostatic Patch for Air Leak Management: Results from a Decade of Pulmonary Resections Using Propensity-Score Weighting.

Interdisciplinary cardiovascular and thoracic surgery·2025
Same author

Unfolding ARF and ARL GTPases: from biophysics to systems-level insights.

Frontiers in molecular biosciences·2025
Same author

Proximity-based proteomics (BioID) uncovers the Rho GTPase interactome in kidney podocytes.

Frontiers in cell and developmental biology·2025

Related Experiment Video

Updated: Jul 7, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
07:27

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

Left upper lobe pulmonary sequestration.

Pascal Berna1, João Carlos das Neves Pereira, Jean-François Coté

  • 1Thoracic Surgery Department, Georges Pompidou European Hospital, 20-40 rue Leblanc, 75015 Paris, France.

Interactive Cardiovascular and Thoracic Surgery
|February 21, 2008
PubMed
Summary
This summary is machine-generated.

A rare case of pulmonary sequestration in the upper lobe was identified in a 64-year-old woman. This developmental lung disease, typically found in the lower lobes, presents diagnostic challenges and may be underestimated.

More Related Videos

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
11:17

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

Related Experiment Videos

Last Updated: Jul 7, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
07:27

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
11:17

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

Area of Science:

  • Thoracic Surgery
  • Pulmonary Medicine
  • Developmental Pathology

Background:

  • Pulmonary sequestration is a rare congenital lung malformation.
  • It typically presents as a non-functional lung segment with abnormal blood supply.
  • Lower lobe locations are most common, with upper lobe presentation being uncommon.

Observation:

  • A 64-year-old non-smoking female presented with a left upper lobe mass.
  • Initial video-thoracoscopic wedge resection was performed.
  • Intraoperative frozen section could not exclude neoplastic disease, necessitating a lobectomy.

Findings:

  • Microscopic analysis confirmed a typical pulmonary sequestration pattern.
  • Key features included systemic arterial supply to the sequestered segment.
  • The upper lobe location was noted as unusual for this condition.

Implications:

  • This case highlights the diagnostic difficulties associated with upper lobe pulmonary sequestration.
  • The uncommon location may lead to underdiagnosis or misdiagnosis.
  • Further research is warranted to understand the clinical significance and management of upper lobe sequestration.