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Stroke in the young: relationship with iron deficiency anemia and thrombocytosis

R Basak1, Am Chowdhury, Le Fatmi

  • 1Dhaka Medical College Hospital, Dhaka, Bangladesh.

Mymensingh Medical Journal : MMJ
|February 21, 2008
PubMed

Insights

Pediatric stroke is complex due to developmental differences. This case highlights iron deficiency anemia with thrombocytosis as a cause of stroke in a young boy.

Area of Science:

  • Pediatric Neurology
  • Hematology
  • Pediatric Stroke

Background:

  • Stroke recognition and treatment in children present unique challenges due to developmental variations compared to adults.
  • Pediatric stroke requires careful etiological investigation, considering factors distinct from adult stroke syndromes.

Observation:

  • A young boy experienced sudden right-sided weakness, unconsciousness, and convulsions without preceding fever or trauma.
  • Neurological examination indicated an upper motor neuron lesion affecting the right extremities.
  • Cerebral CT imaging revealed diffuse hypodense areas in the frontoparietal regions.

Findings:

  • Complete blood count and iron profile tests identified iron deficiency anemia with thrombocytosis.
  • The etiological explanation for the child's stroke was determined to be thrombosis secondary to thrombocytosis, which was itself a complication of iron deficiency anemia.

Implications:

  • This case underscores the importance of considering hematological abnormalities, such as iron deficiency anemia with secondary thrombocytosis, in the differential diagnosis of pediatric stroke.
  • Early identification and management of these underlying conditions are crucial for preventing recurrent thrombotic events in children.
  • Further research into the specific mechanisms linking iron deficiency anemia and thrombotic stroke in pediatric populations is warranted.

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