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Updated: Jul 7, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
Prenatal diagnosis of Ebstein's anomaly using spatio-temporal image correlation (STIC) and inversion mode
Edward Araujo Júnior1, Luiz Cláudio de Bussamra, Fernanda Silveira Bello Barros
1Department of Obstetrics, São Paulo Federal University (UNIFESP-EPM), São Paulo, SP, Brazil. araujojred@terra.com.br
Background:
Ebstein's anomaly is a rare cardiac defect where the septal and posterior leaflets are displaced, towards the right ventricle. The leaflets are dysplastic and stuck to the ventricular wall. Its antenatal diagnosis is usually made through bidimensional echocardiography, which also has prognostic value. Recently, the technological breakthrough of three-dimensional ultrasound (3D-US) offered new diagnostic tools for congenital heart defects, less dependent on the ultrasonographer experience, when compared to two-dimensional ultrasound (2D-US). The spatio-temporal image correlation (STIC) technique allows the acquisition of the fetal heart volume and its structures as a 4D cineloop sequence showing the complete cardiac cycle. Inversion mode is a new image analysis tool for the examination of fluid-filled fetal structures that inverts the gray scale.
Case Report:
We present a case of Ebstein's anomaly diagnosed at 26 weeks of pregnancy through bidimensional echocardiography. We emphasize its main findings in 3D-US using the STIC and inversion mode techniques.

