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Clinical utility of hybrid SPECT-CT in endocrine neoplasia
Chirag N Patel1, Fahmid U Chowdhury, Andrew F Scarsbrook
1Department of Radiology, St. James' University Hospital, Beckett St., Leeds LS9 7TF, United Kingdom. chirag.patel@leedsth.nhs.uk
Objective:
Imaging of endocrine neoplasms often involves a combination of anatomic and functional techniques including sonography, CT, MRI, and scintigraphy. Recent technologic advances have enabled hybrid imaging using SPECT-CT, which combines anatomic and functional techniques to allow accurate localization of tumors, increased detection of recurrent and metastatic disease, and exclusion of physiologic uptake.
Conclusion:
SPECT-CT provides improved specificity and diagnostic confidence helping to guide conventional management and assess suitability for targeted radionuclide therapy.