Related Experiment Video

Updated: Jul 7, 2026

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
06:08

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging

Published on: February 7, 2014

Pulse wave velocity is associated with metabolic syndrome components in CAPD patients

Xing-wei Zhe1, Jing Zeng, Xin-kui Tian

  • 1Division of Nephrology, Peking University Third Hospital, Beijing, PR China.

American Journal of Nephrology
|February 22, 2008
PubMed

Insights

Metabolic syndrome traits are linked to increased arterial stiffness in continuous ambulatory peritoneal dialysis patients. This association suggests metabolic syndrome criteria can help predict cardiovascular disease risk in this population.

Area of Science:

  • Nephrology
  • Cardiology
  • Metabolic Diseases

Background:

  • Cardiovascular disease (CVD) accounts for 40-50% of deaths in dialysis patients.
  • Pulse wave velocity (PWV) is a marker of arterial stiffness and CVD risk.
  • Metabolic syndrome (MetS) components are known cardiovascular risk factors.

Purpose of the Study:

  • To investigate the association between components of the metabolic syndrome (MetS) and pulse wave velocity (PWV) in continuous ambulatory peritoneal dialysis (CAPD) patients.
  • To assess PWV as an indicator of vascular status in CAPD patients with varying MetS traits.

Main Methods:

  • A cross-sectional study involving 148 prevalent CAPD patients.
  • Patients were grouped based on the number of MetS traits (No MetS, Risk of MetS, MetS). Waist circumference was excluded due to PD effects.
  • Carotid-femoral PWV (C-F PWV) was used to measure aortic stiffness.

Main Results:

  • The number of MetS traits showed a positive association with C-F PWV (r=0.301, p<0.01).
  • MetS traits also correlated with increased pulse pressure, systolic blood pressure, and serum albumin.
  • Multivariate regression identified age and MetS score as independent determinants of PWV.

Conclusions:

  • Metabolic syndrome traits are significantly associated with increased arterial stiffness (C-F PWV) in CAPD patients, even after adjusting for confounders.
  • The findings support the utility of MetS criteria for predicting cardiovascular disease risk in patients undergoing peritoneal dialysis.
Abstract

More Related Videos

Ultrasound-based Pulse Wave Velocity Evaluation in Mice08:07

Ultrasound-based Pulse Wave Velocity Evaluation in Mice

Published on: February 14, 2017

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome06:04

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

Published on: September 27, 2024

Related Concept Videos

Pulse01:05

Pulse

The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls between...
Pulse amplitude and quality01:17

Pulse amplitude and quality

Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.
Pulse01:16

Pulse

When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical indicator...
Cardiovascular System Abnormal Findings I: Inspection and Palpation01:29

Cardiovascular System Abnormal Findings I: Inspection and Palpation

In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection
Dysrhythmias III: Characteristics of Dysrhythmias01:29

Dysrhythmias III: Characteristics of Dysrhythmias

Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per minute.