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Related Experiment Video

Updated: Jul 7, 2026

Ultrasound Assessment of Endothelial Function: A Technical Guideline of the Flow-mediated Dilation Test

Ultrasound Assessment of Endothelial Function: A Technical Guideline of the Flow-mediated Dilation Test

Published on: April 27, 2016

Correlation between flow-mediated dilation and erectile dysfunction.

Imre Kovács¹, Albert Császár, Janos Toth

¹Endothelium Study Group, Markusovszky Hospital, Szombathely, Budapest, Hungary.

Journal of Cardiovascular Pharmacology

|February 22, 2008

Summary

This summary is machine-generated.

Erectile dysfunction correlates with reduced brachial artery flow-mediated dilation, indicating endothelial dysfunction. This suggests erectile dysfunction may signal early peripheral vascular disease.

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Ultrasound Assessment of Endothelial Function: A Technical Guideline of the Flow-mediated Dilation Test

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Published on: April 27, 2016

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

Published on: September 27, 2024

Area of Science:

Cardiovascular Medicine
Urology
Vascular Biology

Background:

Endothelial dysfunction is implicated in various cardiovascular diseases.
Erectile dysfunction (ED) may be an early indicator of systemic vascular health.

Purpose of the Study:

To investigate the correlation between brachial artery flow-mediated dilation (FMD) and erectile function.
To explore the potential of ED as an early marker for peripheral vascular disease.

Main Methods:

56 male patients with ED underwent brachial artery FMD measurements.
Patients were stratified by ED severity using the International Index of Erectile Dysfunction.
Flow-mediated dilation (FMD) was assessed as a measure of endothelial function.

Main Results:

A significant reduction in FMD was observed with increasing ED severity.
Positive correlations were found between endothelial function and erectile function.
Higher sildenafil dosage requirements correlated with greater ED severity.

Conclusions:

Vascular endothelial dysfunction may contribute to erectile dysfunction.
Erectile dysfunction could serve as an early indicator of peripheral vascular disease.