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The progress on genetic analysis of nasopharyngeal carcinoma
Xiaofeng Zhou1, Jing Cui, Virgilia Macias
1Center for Molecular Biology of Oral Diseases, College of Dentistry, Graduate College, UIC Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA.
Abstract:
Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world, but is one of the most common cancers in Southeast Asia. Both genetic and environmental factors contribute to the tumorigenesis of NPC, most notably the consumption of certain salted food items and Epstein-Barr virus infection. This review will focus on the current progress of the genetic analysis of NPC (genetic susceptibilities and somatic alterations). We will review the current advances in genomic technologies and their shaping of the future direction of NPC research.