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Development and Angiographic Use of the Rabbit VX2 Model for Liver Cancer
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Feline visceral hemangiosarcoma.

W T N Culp1, K J Drobatz, M M Glassman

  • 1Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA. wculp@vet.upenn.edu

Journal of Veterinary Internal Medicine
|February 22, 2008
PubMed
Summary

Feline visceral hemangiosarcoma (HSA) is often multifocal and aggressive, leading to a poor prognosis for cats. Early diagnosis and treatment options for this rare cancer remain limited.

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Area of Science:

  • Veterinary Oncology
  • Comparative Pathology

Background:

  • Feline visceral hemangiosarcoma (HSA) is an uncommon cancer in cats.
  • Clinical progression and outcomes for feline visceral HSA are poorly documented.

Purpose of the Study:

  • To investigate the clinical characteristics, diagnostic findings, and outcomes of feline visceral HSA.
  • To provide insights into the prognosis and treatment of this rare feline tumor.

Main Methods:

  • Retrospective review of medical records from 26 cats with visceral HSA.
  • Multi-institutional data collection and analysis.

Main Results:

  • Common signs include lethargy, anorexia, respiratory distress, and collapse.
  • Anemia (82%) and elevated aspartate transaminase (53%) were frequent findings.

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  • Metastasis to the lungs occurred in 33% of cases; HSA was often multifocal (77%) and located in the liver, intestines, or lymph nodes.
  • Median survival time for treated cats was 77 days.
  • Conclusions:

    • Feline visceral HSA is typically diagnosed as a multifocal disease.
    • The prognosis for cats with visceral HSA is poor, with limited chemotherapy use.
    • Further research is needed to improve outcomes for affected cats.