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Structural lability in stem-loop 1 drives a 5' UTR-3' UTR interaction in coronavirus replication

Lichun Li1, Hyojeung Kang, Pinghua Liu

  • 1Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843-2128, USA.

Journal of Molecular Biology
|February 22, 2008
PubMed
Summary

Coronaviruses utilize a dynamic leader RNA structure (SL1) in their 5' untranslated region (UTR) for subgenomic RNA synthesis. This structure

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RNA Structure

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Different Types of RNA Have the Same Basic Structure
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Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
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RNA Stability

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