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Related Concept Videos

Instrument Calibration01:12

Instrument Calibration

Instrument calibration is essential for ensuring that instruments produce accurate and consistent results. It is vital in manufacturing, healthcare, testing laboratories, and scientific research. Calibration processes are specific to each instrument and help enhance data accuracy. Each instrument has a unique calibration process tailored to its design and function to improve data accuracy.
Analytical Balance Calibration
An analytical balance measures mass and requires regular calibration to...
Absorption of Radiation01:05

Absorption of Radiation

The rate of heat transfer by emitted radiation is described by the Stefan-Boltzmann law of radiation:
Calibration Curves: Linear Least Squares01:20

Calibration Curves: Linear Least Squares

A calibration curve is a plot of the instrument's response against a series of known concentrations of a substance. This curve is used to set the instrument response levels, using the substance and its concentrations as standards. Alternatively, or additionally, an equation is fitted to the calibration curve plot and subsequently used to calculate the unknown concentrations of other samples reliably.
For data that follow a straight line, the standard method for fitting is the linear...
Atomic Absorption Spectroscopy: Interference01:25

Atomic Absorption Spectroscopy: Interference

Interference leads to systematic error in atomic absorption (AA) measurements by enhancing or diminishing the analytical signal or the background. These interferences can be grouped into three main categories: spectral interference, chemical interference, and physical interference.
Spectral interference occurs when signals from other elements or molecules overlap with the analyte signal, falsely elevating or masking the analyte's absorbance. This interference can be corrected using Zeeman,...
Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview01:13

Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview

Attenuated total reflectance (ATR) infrared spectroscopy is a powerful analytical technique used to study the composition of materials. It is widely employed in chemistry, materials science, forensic science, and other fields where sample characterization is required. ATR has several advantages over traditional transmission IR spectroscopy, including the requirement of little to no sample preparation and the ability to analyze a wide range of samples.
The ATR process begins by directing a beam...
Atomic Absorption Spectroscopy: Lab01:21

Atomic Absorption Spectroscopy: Lab

For AAS measurements, samples must be introduced as clear solutions, often requiring extensive preliminary treatment to dissolve materials like soils, animal tissues, and minerals. Common methods for sample preparation include treatment with hot mineral acids, wet ashing, combustion in closed containers, high-temperature ashing, or fusion with reagents.
 Solutions containing organic solvents, such as low-molecular-mass alcohols, esters, or ketones, enhance absorbances by increasing nebulizer...

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Related Experiment Video

Updated: Jul 7, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
06:33

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Published on: July 29, 2013

Absorption and attenuation in soft tissues. I. Calibration and error analyses.

K J Parker1, M E Lyons

  • 1Dept. of Electr. Eng., Rochester Univ., NY.

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
|January 1, 1988
PubMed
Summary

New methods improve error estimation for ultrasound absorption and attenuation measurements. Accurate peak intensity calibration using radiation force reduces uncertainty, enhancing the reliability of absorption coefficient and insertion loss data.

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Area of Science:

  • Ultrasound physics
  • Acoustic measurements
  • Metrology

Background:

  • Accurate error estimation is crucial for reliable ultrasound measurements.
  • Determining peak intensity in focused ultrasound beams presents significant challenges.
  • Existing methods for absorption and attenuation measurements have limitations in precision.

Purpose of the Study:

  • To develop robust error estimation techniques for ultrasound pulse decay absorption and radiation force insertion loss measurements.
  • To establish a precise in situ method for calibrating peak focal intensity.
  • To quantify uncertainties associated with these acoustic measurements.

Main Methods:

  • Developed an intensity calibration using radiation force measurement of total power and main lobe beam patterns.
  • Utilized embedded thermocouples and short ultrasound bursts for calibration.
  • Employed a theoretical extension of main-lobe beam patterns to estimate peak focal intensity, accounting for sidelobes.
  • Analyzed uncertainties in repeated radiation force insertion loss measurements.

Main Results:

  • Achieved in situ peak intensity estimates with typical uncertainty <5%.
  • Resulting absorption coefficient uncertainty is estimated at 10%.
  • Demonstrated that errors of <=3% are achievable for insertion loss measurements on homogeneous materials.

Conclusions:

  • The developed methods provide accurate error estimation for key ultrasound parameters.
  • The radiation force-based intensity calibration enhances measurement reliability.
  • The approach is suitable for precise acoustic characterization in various applications.