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Impact of anti-tuberculosis therapy on plasma zinc status in childhood tuberculosis
M R Boloorsaz1, S Khalilzadeh, A R Milanifar
1National Research Institute of Tuberculosis and Lung Disease, Massih Daneshvari Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
Abstract:
This study compared plasma zinc levels in 15 children with active pulmonary tuberculosis, 15 malnourished children and 15 healthy children. Mean plasma zinc concentrations in children with tuberculosis (71.7 microg/dL) were not significantly different than the other 2 groups (72.5 and 76.9 microg/dL). The zinc status of the children with tuberculosis was evaluated after 2 months and 4 months of DOTS therapy. The serum zinc level during anti-tuberculosis therapy decreased after 1 month and then recovered to the initial level after 4 months of treatment.
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