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Updated: Jul 7, 2026

Whole-cell MALDI-TOF Mass Spectrometry is an Accurate and Rapid Method to Analyze Different Modes of Macrophage Activation
11:25

Whole-cell MALDI-TOF Mass Spectrometry is an Accurate and Rapid Method to Analyze Different Modes of Macrophage Activation

Published on: December 26, 2013

MALDI-TOF mass spectrometry compatible inactivation method for highly pathogenic microbial cells and spores

Peter Lasch1, Herbert Nattermann, Marcel Erhard

  • 1P25, ZBS2, and ZBS4, Robert Koch-Institut, Nordufer 20, 13353 Berlin, Germany. LaschP@rki.de

Analytical Chemistry
|February 23, 2008
PubMed
Summary

A new trifluoroacetic acid (TFA) inactivation method effectively inactivates vegetative cells and spores of high-risk microorganisms. This rapid protocol is compatible with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for microbial identification.

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