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Updated: Jul 7, 2026
14:14
Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Aortic valve replacement with simultaneous chest wall reconstruction for radiation-induced sarcoma
Anand Sachithanandan1, Uday Dandekar, Robert Grimer
1Department of Cardiothoracic Surgery, Queen Elizabeth Hospital, University Hospital Birmingham NHS Trust, United Kingdom.
Journal of Cardiac Surgery
|February 23, 2008
Summary
Radiation-induced chest wall sarcomas are rare but serious complications following breast cancer radiotherapy. This case highlights a successful simultaneous surgical approach for aortic valve replacement and sarcoma removal, followed by chest wall reconstruction.
Area of Science:
- Oncology
- Cardiovascular Surgery
- Thoracic Surgery
Background:
- Sarcomas are rare but aggressive malignancies.
- Radiation-induced sarcomas are a known, albeit infrequent, complication of radiotherapy.
- Breast cancer radiotherapy can lead to secondary chest wall sarcomas with poor prognoses.
Observation:
- A patient with prior mantle radiotherapy for breast carcinoma developed a chest wall sarcoma.
- The patient also had severe aortic stenosis requiring intervention.
Findings:
- A simultaneous surgical approach was performed, involving aortic valve replacement (AVR) and complete excision of the radiation-induced sarcoma.
- Chest wall reconstruction utilized a composite marlex cement plate combined with a pedicled latissimus dorsi muscle flap.
Implications:
- This case demonstrates the feasibility of a combined surgical strategy for managing rare radiation-induced sarcomas alongside other critical cardiac conditions.
- The successful reconstruction highlights effective multidisciplinary management for complex thoracic reconstruction following oncologic treatment.
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