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Updated: Jul 7, 2026

A Protocol for Explant Cultures of IDH1-mutant Diffuse Low-grade Gliomas
Published on: May 9, 2025
Demyelination or low-grade glioma? A diagnostic dilemma
Rahul Gupta1, Sandeep Mohindra, Kirti Gupta
1Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India. rahulguptaneuro@gmail.com
Background:
Demyelination is a neurologic disease, usually diagnosed on the basis of clinical symptomatology and radiologic studies. Rarely, both may be deceiving and masquerading a neoplastic lesion or vice versa.
Case Description:
In the present communication, we describe 2 cases with similar clinical profiles and radiologic pictures, but which turn out to be contrasting pathologic diagnoses.
Conclusions:
We emphasize on histopathologic proof before initiating definitive therapy.

