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Prognosis after off-pump coronary artery bypass in patients receiving hemodialysis
Noriyuki Murai1, Koujirou Kodera, Akifumi Sasaki
1Department of Cardiovascular Surgery, Tokyo Women's Medical University, Tokyo, Japan.
Insights
Off-pump coronary artery bypass grafting (OPCAB) is safe for hemodialysis (HD)-dependent patients, showing similar perioperative outcomes and improved long-term survival rates compared to non-HD patients.
Area of Science:
- Cardiovascular Surgery
- Nephrology
- Oncology
Background:
- Coronary artery disease is prevalent in patients requiring hemodialysis.
- Surgical risk stratification in hemodialysis patients undergoing cardiac surgery is crucial.
Purpose of the Study:
- To evaluate the safety and efficacy of off-pump coronary artery bypass grafting (OPCAB) in hemodialysis-dependent patients.
- To compare perioperative and long-term outcomes of OPCAB between hemodialysis (HD) and non-HD patient groups.
Main Methods:
- Retrospective analysis of isolated OPCAB procedures from 2000 to 2006.
- Comparison of perioperative data between HD (n=39) and non-HD (n=60) groups.
- Examination of long-term survival in the HD group.
Main Results:
- Complete all-arterial revascularization was less frequent in the HD group.
- Mortality, operative time, ICU stay, hospital stay, and need for transfusions were similar between groups.
- Actuarial 1- and 5-year survival rates in the HD group were 80% and 70%, respectively.
Conclusions:
- Off-pump coronary artery bypass grafting (OPCAB) is a safe procedure for hemodialysis-dependent patients.
- OPCAB demonstrates improved long-term survival in patients requiring hemodialysis.
Purpose:
This study was performed to evaluate the perioperative and long-term results of off-pump coronary artery bypass grafting (OPCAB) in hemodialysis (HD)-dependent patients.
Methods:
We retrospectively analyzed the results of isolated OPCAB performed at Tokyo Women's University Medical Center East from February 27, 2000, to May 12, 2006. Perioperative data for patients receiving HD (group HD, n=39) were compared with data from patients not receiving HD (group noHD, n=60). The long-term results of group HD also were examined.
Results:
Group HD consisted of 34 males and 5 females with a mean age of 63.2+/-10.2 years. The percentage of patients in group HD with complete all-arterial revascularization was significantly lower than in group noHD. However, the mortality rate, number of distal anastomoses, operative time, intensive care unit (ICU) stay, hospital stay, bleeding during surgery, blood transfusions, intubation time, intra-aortic balloon pumping use, and emergency ratio were similar in the two groups. During a mean follow-up of 27.0+/-13.7 months, the actuarial 1-and 5-year survival rates of group HD were 80% and 70%, respectively.
Conclusion:
In patients receiving HD, OPCAB is safe and improves survival.
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