Related Experiment Video
Updated: Jul 7, 2026
10:28
Isolation, Expansion, and Adipogenic Induction of CD34+CD31+ Endothelial Cells from Human Omental and Subcutaneous Adipose Tissue
Published on: July 17, 2018
[Adiponectin concentrations during menstrual cycle].
Rosa E Galván1, Lourdes Basurto, Renata Saucedo
1Unidad de Investigación en Enfermedades Endocrinas, Hospital de Especialidades del Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, DF.
Ginecologia Y Obstetricia De Mexico
|February 26, 2008
Summary
Adiponectin levels fluctuate during the menstrual cycle, with the lowest concentrations observed in the postovulatory phase. These changes may relate to metabolic processes like insulin resistance in women.
Area of Science:
- Endocrinology
- Metabolic Research
- Reproductive Science
Context:
- Adiponectin, a key adipokine, influences insulin sensitivity.
- Understanding hormonal impacts on metabolic markers is crucial for women's health.
- The menstrual cycle involves dynamic hormonal shifts affecting various physiological processes.
Purpose:
- To investigate adiponectin concentrations across the menstrual cycle phases.
- To examine the relationship between adiponectin, 17-beta estradiol, and progesterone.
- To assess potential links between adiponectin variations and insulin resistance.
Summary:
- This longitudinal study monitored 30 women, measuring adiponectin, estradiol, and progesterone throughout their menstrual cycles.
- Adiponectin levels were significantly lower during the postovulatory phase compared to follicular and ovulatory phases.
- No significant correlation was found between adiponectin and either 17-beta estradiol or progesterone levels.
Impact:
- Adiponectin levels exhibit cyclical variation in women, independent of estradiol and progesterone.
- Lower postovulatory adiponectin may indicate a potential link to transient insulin resistance.
- Findings contribute to understanding the interplay between reproductive hormones and metabolic health in women.
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At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
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