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A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats
Published on: March 23, 2018
"Orpheus" cardiopulmonary bypass simulation system
Richard W Morris1, David A Pybus
1Department of Anaesthesia, St. George Hospital, Gray Street, Kogarah, NSW 2217, Australia. rcmorris@bigpond.net.au
The Journal of Extra-Corporeal Technology
|February 26, 2008
Summary
This paper introduces a high-fidelity simulation system for training perfusionists. The system accurately models cardiopulmonary bypass events and drug pharmacokinetics, enhancing critical care education.
Area of Science:
- Medical Simulation
- Cardiopulmonary Perfusion Technology
Background:
- Perfusionists require specialized training for complex cardiopulmonary bypass procedures.
- Current training methods may not fully replicate the dynamic and critical nature of intraoperative events.
Purpose of the Study:
- To describe a high-fidelity simulation system for perfusionist training and continuing education.
- To detail the system's components, capabilities, and potential applications in enhancing perfusion practice.
Main Methods:
- Development of a system including a hydraulic simulator, electronic interface, and real-time computer models.
- Integration with institutional operating theatre equipment (heart-lung machine, monitoring systems).
- Incorporation of a sophisticated blood gas model and pharmacokinetic drug models.
Main Results:
- The simulator accurately reproduces normal and abnormal cardiopulmonary bypass events.
- A detailed blood gas model predicts oxygenator behavior, with outputs updated every 500 milliseconds.
- Pharmacokinetic profiles for various drugs (vasoconstrictors, vasodilators, etc.) are modeled.
Conclusions:
- The simulation system offers a realistic environment for perfusionist skill training.
- It supports the development of crisis management protocols and evaluation of new techniques.
- This technology has significant potential for perfusionist certification and accreditation.

