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Related Experiment Video

Updated: Jul 7, 2026

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5

Published on: April 26, 2019

Ileocecal interposition for Hirschsprung's disease: a case report.

F Penninckx¹, W Van den Eynde, A D'Hoore

¹UZ Gasthuisberg - Abdominal Surgery, Leuven, Belgium. freddy.penninckx@uz.kuleuven.ac.be

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland

|February 26, 2008

Summary

Ileocecal interposition (ICI) is an effective rescue surgery for complex Hirschsprung disease when standard approaches fail. This technique preserves bowel length and creates a functional neorectal reservoir, yielding excellent long-term results.

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Murine Ileocolic Bowel Resection with Primary Anastomosis

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Published on: October 29, 2014

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Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5

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Murine Ileocolic Bowel Resection with Primary Anastomosis

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Area of Science:

Pediatric Surgery
Gastroenterology
Colorectal Surgery

Background:

Congenital aganglionosis, or Hirschsprung disease, affects the colon's nerve supply, leading to functional obstruction.
Standard surgical treatments may be challenging in cases with extensive aganglionosis or prior surgical interventions like colostomy.
The interruption of the paracolic arcade during prior colostomy construction complicated the surgical approach in this case.

Observation:

A 14-month-old girl with congenital aganglionosis up to the sigmoid colon underwent an ileocecal interposition (ICI).
The left colon could not be mobilized due to a compromised paracolic arcade from a previous colostomy.
The patient had a history of a preceding colostomy construction.

Findings:

The ileocecal interposition (ICI) procedure was performed as a rescue intervention.
Fourteen years post-reconstruction, the patient exhibited excellent functional outcomes.
Daily bowel movements were 1-2, with normal continence for flatus and stool.

Implications:

Ileocecal interposition (ICI) serves as a viable rescue procedure for complex cases of Hirschsprung disease.
This technique maximizes the use of normally innervated bowel, preserving functional length.
ICI creates a neorectal reservoir, contributing to successful long-term functional results and improved quality of life.