Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diastolic function in valvular heart disease.

O M Hess1, L Felder, H P Krayenbuehl

  • 1Department of Internal Medicine, Medical Policlinic, Cardiology, University Hospital, Zurich, Switzerland.

Herz
|April 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcome of empirical or targeted antifungal therapy after antifungal prophylaxis in febrile neutropenia.

Annals of hematology·2016
Same author

Insulin inhibition by serum of insulin resistant patient.

The Journal of clinical endocrinology and metabolism·2010
Same author

Primary systemic amyloidosis; jaundice as a rare accompaniment.

The American journal of the medical sciences·2010
Same author

[Is resting heart rate a cardiovascular risk factor?].

Praxis·2008
Same author

ECG-triggered skeletal muscle stimulation improves hemodynamics and physical performance of heart failure patients.

The International journal of artificial organs·2008
Same author

ECG-triggered muscular counterpulsation for treatment of low cardiac output.

The International journal of artificial organs·2007
Same journal

[Advancing cardiovascular prevention : Evidence-based design of healthy and sustainable food environments].

Herz·2026
Same journal

[Effects of air pollution on cardiovascular health].

Herz·2026
Same journal

[Heart and climate].

Herz·2026
Same journal

Multidimensional psychosocial screening in routine cardiac care: preliminary findings from a cross-sectional survey.

Herz·2026
Same journal

[Noise and the heart].

Herz·2026
Same journal

[The cardiovascular exposome: areas of action for prevention and practical cardiology].

Herz·2026
See all related articles

Diastolic dysfunction in valvular heart disease involves impaired relaxation and stiffness, potentially worsening after surgery. This cardiac issue can be a primary problem or revealed by exercise-induced pressure changes.

Area of Science:

  • Cardiology
  • Cardiac Physiology

Background:

  • Diastolic dysfunction in valvular heart disease presents with impaired isovolumic relaxation and increased myocardial stiffness.
  • These abnormalities can coexist with systolic dysfunction and stem from mechanisms like increased wall stress and altered myocardial structure.

Purpose of the Study:

  • To explore the mechanisms and clinical implications of diastolic dysfunction in valvular heart disease.
  • To understand the impact of valve replacement surgery on diastolic function.

Main Methods:

  • The study reviews existing literature and clinical observations regarding diastolic dysfunction in valvular heart disease.
  • Analysis of patient data focusing on myocardial structure, filling pressures, and responses to exercise.

Main Results:

Related Experiment Videos

  • Postoperative valve replacement may paradoxically worsen diastolic dysfunction due to myocardial remodeling and increased interstitial fibrosis.
  • Diastolic dysfunction can persist or manifest during dynamic exercise, indicated by rising left ventricular filling pressures.

Conclusions:

  • Diastolic dysfunction is a significant component of valvular heart disease, influenced by surgical interventions.
  • Exercise testing can unmask latent diastolic dysfunction, highlighting its clinical relevance in postoperative patients.