A body-weight-based method to estimate inorganic arsenic body burden through tilapia consumption in Taiwan

In the present study, a stage-classified exposure model is developed to better characterize long-term arsenic (As) accumulation of both genders of children, adolescents, and adults through tilapia consumption in Taiwan. Ingestion rate as well as elimination rate of As are treated dynamically and are used to parameterize the stage-classified accumulation model. Model simulations are carried out to produce temporal changes of As body burden of the residents who consume tilapia from blackfoot disease (BFD)-endemic area in three major cities in Taiwan. The model presented here can be served as a strong framework for refining human health risk assessments through fish consumption.