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Ocular rigidity evaluation after photorefractive keratectomy: an experimental study.
George D Kymionis1, Vasilios F Diakonis, George Kounis
1Vardinoyannion Eye Institute of Crete, University of Crete, Medical School, Dept of Ophthalmology, 71110 Heraklion, Crete, Greece. kymionis@med.uoc.gr
Journal of Refractive Surgery (Thorofare, N.J. : 1995)
|February 27, 2008
Summary
Photorefractive keratectomy (PRK) did not significantly change ocular rigidity in rabbit eyes. This study found no significant difference in ocular rigidity measurements after PRK compared to control eyes.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Ocular Biomechanics
Background:
- Photorefractive keratectomy (PRK) is a common refractive surgery.
- Changes in corneal biomechanics after PRK are not fully understood.
- Ocular rigidity is a key biomechanical parameter of the eye.
Purpose of the Study:
- To investigate the effect of PRK on ocular rigidity in a rabbit model.
- To evaluate in vivo changes in ocular rigidity coefficient post-PRK.
Main Methods:
- PRK was performed on one eye of 8 rabbits for -10.00 D correction.
- The fellow eye served as a control.
- Ocular rigidity was measured by saline injection into the anterior chamber and IOP monitoring.
Main Results:
- Preoperative corneal thickness was similar between PRK and control eyes.
- No statistically significant difference was found in the ocular rigidity coefficient between PRK-treated and control eyes.
- The mean rigidity coefficient was 0.42 +/- 0.12 mmHg/microL for PRK eyes and 0.47 +/- 0.12 mmHg/microL for control eyes (P = .121).
Conclusions:
- PRK did not significantly alter ocular rigidity measurements in this rabbit model.
- These findings suggest PRK may not substantially impact overall ocular biomechanics.
- Further research may explore long-term effects or different surgical parameters.
