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Bicyclic polyketide lactones from Chinese medicinal ants, Polyrhacis lamellidens
Zhi-Hong Jiang1, Qing-Xiong Yang, Takashi Tanaka
1School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, People's Republic of China. zhjiang@hkbu.edu.hk
Abstract:
Two new bicyclic polyketide lactones, polyrhacitides A ( 1) and B ( 2), were isolated from Chinese medicinal ants, Polyrhacis lamellidens, which have been used as an effective therapeutic agent to treat rheumatoid arthritis and hepatitis in China. Their absolute structures were elucidated on the basis of spectroscopic analyses and chemical evidence. The occurrence of polyketides with similar structures in plants of the Lamiaceae, Lauraceae, and Staphyleaceae indicates their significance in the study of chemical ecology.
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