[Evaluation of the activity of the inflammatory process in ankylosing spondyloarthritis]

A total of 139 patients with ankylosing spondyloarthritis (AS) (65 with the central form of the disease and 74 with the peripheral one) were examined to clarify the signs corresponding to the activity of the inflammatory process. To determine the degree of the inflammatory process activity in AS irrespective of its clinical forms the same laboratory indices can be used. With the central form of the disease some indices directly correlate with the markedness of pain and constraint in the spine. The activity of the process in this variant clearly reflects the level of circulating immune complexes (CIC) and IgG. With the peripheral form of the disease some other indices are found to be most sensitive. The presence of some difference in combination of laboratory signs reflecting the activity of the inflammatory process of AS in both forms can evidence the heterogeneity of the mechanisms of inflammation.