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Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
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Related Experiment Video

Updated: Jul 7, 2026

Transition of Farm Pigs to Research Pigs using a Designated Checklist followed by Initiation of Clicker Training - a Refinement Initiative
07:59

Transition of Farm Pigs to Research Pigs using a Designated Checklist followed by Initiation of Clicker Training - a Refinement Initiative

Published on: August 21, 2021

Food Animal Practice. Preface

Sandra Godden1, Sheila M McGuirk

  • 1Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, 225 VMC, 1365 Gortner Avenue, St. Paul, MN 55108, USA. godde002@umn.edu

The Veterinary Clinics of North America. Food Animal Practice
|February 27, 2008
PubMed
Summary

No abstract available in PubMed .

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